New drug candidates in tuberculosis treatment

New drug candidates for hepatitis C treatment

The more advantageous hepatitis C virus (HCV) inhibitors (most of them incorporating polysubstituted prolines or pyrrolidines) are detailed in this paper. The improvement of current treatments by combination of antiviral drugs is the driving force of this race to reduce the fast proliferation of this virus. The enhancement of efficiency in short periods of treatment is crucial in the economical...

New drug candidates and therapeutic targets for tuberculosis therapy.

Despite advances in chemotherapy and the BCG (Bacillus Calmette-Guérin) vaccine, tuberculosis remains a significant infectious disease. Although it can be cured, the therapy takes at least 6-9 months, and the laborious and lengthy treatment brings with it dangers of noncompliance, significant toxicity and drug resistance. The increasing emergence of drug resistance and the problem of mycobacter...

Repurposing of drug candidates for treatment of skin cancer

Skin cancers are highly prevalent malignancies that affect millions of people worldwide. These include melanomas and nonmelanoma skin cancers. Melanomas are among the most dangerous cancers, while nonmelanoma skin cancers generally exhibit a more benign clinical pattern; however, they may sometimes be aggressive and metastatic. Melanomas typically appear in body regions exposed to the sun, alt...

Modern Drug Treatment in Tuberculosis

M.D. (Pp. xii + 566; figs. 415. 144s.) London: Bailliere, Tindall & Cox, 1958. THIS work covers every conceivable aspect of obstruction in the gastro-intestinal tract from the cesophagus to the anal canal in a truly encycloprdic manner. The book contains a tremendous amount of information and approximately 1,700 references in the bibliography. It is refreshing here to note that the authors incl...

Modern Drug Treatment in Tuberculosis